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Results for "

retinal neovascularization

" in MedChemExpress (MCE) Product Catalog:

4

Inhibitors & Agonists

1

Peptides

Cat. No. Product Name Target Research Areas Chemical Structure
  • HY-108544
    INCA-6
    1 Publications Verification

    Triptycene-1,4-quinone

    		 Nuclear Factor of activated T Cells (NFAT) Cardiovascular Disease
    INCA-6 (Triptycene-1,4-quinone) is a cell-permeable NFAT inhibitor. INCA-6 specifically blocks targeting of NFAT(P) substrate to the  calcineurin (CN) phosphatase site and is an effective inhibitor of CN-NFAT signaling .
    INCA-6
  • HY-116030
    JNJ-26076713

    		Integrin Metabolic Disease
    JNJ-26076713 is a potent and orally active alpha V integrin antagonist with IC50 values of 2.3 nM and 6.3 nM for alpha(V)beta(3) and alpha(V)beta(5), respectively. JNJ-26076713 inhibits retinal neovascularization .
    JNJ-26076713
  • HY-P4253
    Arginyl-Glutamine

    		VEGFR Cardiovascular Disease
    Arginyl-Glutamine is a dipeptide that can decrease VEGF levels and inhibit retinal neovascularization in a mouse model of oxygen-induced retinopathy .
    Arginyl-Glutamine
  • HY-125639
    (rac)-AR-13503

    (rac)-AR-13324 M1 metabolite

    		 PKC ROCK Cardiovascular Disease
    (rac)-AR-13503 ((rac)-AR-13324 M1 metabolite) is the isoform of AR-13503 (HY-12798C). AR-13503 a ROCK/PKC inhibitor, inhibiting angiogenesis and enhancing retinal pigment epithelium (RPE) permeability. AR-13503 also inhibits the formation of aberrant neovascularization (NV) in oxygen-induced retinopathy (OIR) model in mice .
    (rac)-AR-13503

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